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Product name:
Ezetex
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Generic name:
Ezetimibe
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Dosage form:
Oral tablets
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Packaging:
Box of 3 blisters of 10 tablets.
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Drug Category:
Cardiovascular
Indications:
Ezetimibe is an inhibitor of intestinal cholesterol (and related phytosterol) absorption indicated as an adjunct to diet to:
Reduce elevated total-C, LDL-C, and Apo B in patients with primary hyperlipidemia, alone or in combination with an HMG-CoA reductase inhibitor (statin).
Reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia in combination with fenofibrate.
Reduce elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia (HoFH), in combination with atorvastatin or simvastatin.
Reduce elevated sitosterol and campesterol in patients with homozygous sitosterolemia (phytosterolemia).
Dosage and Administration:
Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
Continue taking your other cholesterol lowering medicines unless your doctor tells you to stop.
Before starting ezetimibe, you should be on a diet to lower your cholesterol.
You should keep on this cholesterol lowering diet whilst taking ezetimibe.
Take ezetimibe at any time of the day. You can take it with or without food.
If your doctor has prescribed ezetimibe along with a statin, both medicines can be taken at the same time. In this case, please read the dosage instructions in the package leaflet of that particular medicine.
If your doctor has prescribed ezetimibe along with another medicine for lowering cholesterol containing the active ingredient colestyramine or any other medicine containing bile acid sequestrant, you should take ezetimibe at least 2 hours before or 4 hours after taking the bile acid sequestrant.
Contraindication:
Hypersensitivity to the active substance or to any of the excipients.
Statin contraindications apply when ezetimibe is used with a statin:
Active liver disease, which may include unexplained persistent elevations in hepatic transaminase levels.
Women who are pregnant or may become pregnant.
Nursing mothers.
